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Table 4 Variant frequencies of rs80359550, rs180177102 and rs386833395 polymorphisms and their association with breast cancer

From: Association between single nucleotide polymorphisms of DNA repair genes (BRCA1, BRCA2, and PALB2) and breast cancer incidence in a subset of Iranian population

Allele frequency

Mutant allele frequency

Chi-square value

Odds ratio

95% CI

Relative Risk

Z

P-value

rs80359550

(6174delT; BRCA2)

0.004

6.396

0.000

0.000 to 0.659

0.48

2.529

0.011

rs180177102

(c.1592delT; PALB2)

0.002

4.322

0.000

0.000 to 0.630

0.48

2.30

0.021

rs386833395

185delAG (BRCA1)

0

-

1.0 (reference)

0.02 to 53.40

1.0 (reference)

0.028

1.0 (reference)

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Hereditary Cancer in Clinical Practice

ISSN: 1897-4287