Table 1 Genetic study criteria

GROUP I

1 case of cancer in the family

A. Female with breast cancer and synchronous or metachronous ovarian cancer

B. Breast cancer ≤ 35 years old (or ≤ 40 years old in case of noninformative family^a)

C. Bilateral breast cancer (first diagnosed ≤ 40 years old)

D. Triple-negative breast cancer ≤ 50 years old

E. High-grade serous ovarian cancer (or fallopian tube or primary peritoneal)

GROUP II

2 cases of cancer in the family^b

A. Bilateral breast cancer + other breast cancer ≤ 50 years old

B. Male breast cancer + breast or ovarian cancer in females

C. Breast cancer + ovarian cancer

D. Two cases of breast cancer diagnosed ≤ 50 years old

GROUP III

3 cases of cancer in the family^b

≥ 3 cases of breast cancer ± ovarian cancer